Mackie

Mackie ProFX6v3 6-Channel USB Effects Mixer

4.5 (1927 reviews)

Compact 6-channel USB mixer with Onyx preamps, built-in effects, and 24-bit/192kHz recording for live sound and content creation.

$189.99*
In Stock on Amazon.com
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*Price sourced from Amazon.com. Last updated:Jun 20, 2026.Price and availability are subject to change.

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Overview

The Mackie ProFX6v3 is a 6-channel analog mixer built around Mackie's Onyx mic preamps, which provide up to 60dB of gain with ultra-low noise — a key advantage for content creators using condenser or dynamic microphones that demand clean, high-gain amplification. The mixer doubles as a USB audio interface with 2x4 I/O supporting up to 24-bit/192kHz resolution, so it can serve as the central hub for both live mixing and studio recording without needing a separate interface. The 2x4 USB routing allows you to send two independent mixes from your DAW back into the mixer, which is particularly useful when you need to monitor a click track or backing track separately from your main mix.

On the creative side, the ProFX6v3 includes 24 built-in effects ranging from reverbs to delays, controllable via a dedicated effects knob on each channel. A single-knob compressor on the mic channels simplifies dynamic control for vocals and instruments. The included Musician Collection bundle adds 23 DAW plugins and virtual instruments, giving new users a complete production toolkit out of the box. The blend knob for direct monitoring rounds out the feature set, letting you dial in a zero-latency mix of your live input alongside computer playback — essential for tracking overdubs with confidence.

Key Features

Designed for maximum versatility making it perfect for live sound, home recording, content creation, and live streaming with The Musician Collection of 23 plugins and instruments

Equipped with 2 Onyx mic press offering up to 60dB of gain and ultra-low noise performance. Perfect for microphones popular with content creators that require high-gain preamps

Lay down your tracks in incredible 24-bit/ 192kHz quality for the cleanest recordings possible. 2x4 USB I/O allows you to create two custom mixes on your computer to send back in to the mixer, great for situations when you need to monitor specific tracks during playback in addition to the full mix

With 24 different FX options, from reverbs to delays, adding some drama to your sound is easy … easy…. . easy……. . easy (delay, get it?)

With a single knob, you can blend between monitoring your computers output and a direct feed from the mixer. Great for recording overdubs alongside a pre-recorded track

Specifications

Channels
6
Mic Preamps
2 Onyx (up to 60dB gain)
Built-in Effects
24
USB I/O
2x4
Max Recording Resolution
24-bit / 192kHz
Audio Input
XLR
Compression
Single-knob
Connectivity
USB
Power Source
Corded Electric
Weight
2.6 lbs
Voltage
110V

Pros & Cons

👍 Pros

  • Onyx preamps deliver 60dB of clean gain, handling high-gain microphones without added noise
  • 24-bit/192kHz USB recording quality rivals dedicated audio interfaces at this price point
  • 24 built-in effects eliminate the need for external reverb or delay processors
  • Compact form factor fits easily on a small desk or in a portable setup
  • Includes 23 plugins and virtual instruments at no additional cost

👎 Cons

  • Only 2 XLR mic inputs limits use for multi-microphone setups like panel discussions or drum recording
  • 6-channel count may be insufficient as production needs grow
  • No battery or bus power option — requires AC power via the included cord
  • Single-knob compression offers limited control compared to full-featured compressors

Frequently Asked Questions

The ProFX6v3 has 2 Onyx mic preamps with XLR inputs, so you can connect up to 2 microphones simultaneously.
Yes. The ProFX6v3 provides 2x4 USB I/O at up to 24-bit/192kHz, allowing you to record directly into your DAW and send two custom mixes back from your computer.
It comes with The Musician Collection, a bundle of 23 plugins and virtual instruments from Mackie for music production and content creation.
Yes, it features single-knob compression on the mic channels, making it easy to control dynamics without external gear.
The blend knob lets you mix between your computer's audio output and the direct signal from the mixer, which is ideal for recording overdubs alongside a pre-recorded track.