AMD

AMD 100-506008 Radeon Pro WX4100 4GB Graphics Card

4.0 (25 reviews)
Displayport

Half-height 4GB GDDR5 on PCIe 3.0 x16 drives four Mini DisplayPort outputs simultaneously for professional workstation configurations in low-profile chassis.

$121.99*$152.02Save 19%
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*Price sourced from Amazon.com. Last updated:Jun 04, 2026.Price and availability are subject to change.

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Overview

The AMD Radeon Pro WX 4100 is a professional-class workstation GPU in a half-length, low-profile, single-slot form factor — a packaging specification that makes it the only ISV-targeted option for compact OEM workstations where full-height or dual-slot cards cannot physically install. Built on a 128-bit GDDR5 memory bus with 4GB of VRAM, it delivers approximately 96GB/s of memory bandwidth, which covers professional visualization, multi-display desktop management, and CAD viewport rendering at standard workstation resolutions. Core clocks at 1.13GHz base and 1.20GHz boost are conservative by gaming GPU standards but appropriate for the thermal envelope of a single-slot professional cooler. Four Mini DisplayPort outputs enable simultaneous 4K output to four displays from a single card — a capability that would otherwise require multiple GPU slots.

The WX 4100 is positioned for compact professional workstations in engineering, architecture, GIS, and enterprise visualization environments where the priority is ISV-certified stability and multi-display output within a constrained chassis. Its no-auxiliary-power design enables clean integration into OEM small form factor systems that ship without extra PCIe power connectors. The API support stack — OpenCL 2.0, OpenGL 4.5, DirectX 12, Vulkan 1.0 — covers current professional application requirements, and AMD's workstation driver branch prioritizes stability over feature-refresh cadence, which IT managers in managed fleet environments value. For raw GPU-compute throughput or high-polygon real-time rendering, the 128-bit bus and compact thermal solution impose real limits; for its target multi-display professional workstation role, the WX 4100 is well-matched to its specification.

Key Features

Amd Radeon Pro Wx 4100 Graphic Card - 1.13 Ghz Core - 1.20 Ghz Boost Clock - 4 Gb Gddr5 - Pci Express 3.0 X16 - Half-length/low-profile - Single Slot Space Required - 128 Bit Bus Width - Crossfire - Fan Cooler - Opencl 2.0, Opengl 4.5, Directx 12, Vulkan 1.0 - 4 X Mini Displayport - Linux, Pc

Specifications

Brand
AMD
GPU Core Clock Speed
1.13 GHz
GPU Boost Clock Speed
1.20 GHz
Video Memory Size
4 GB
Video Memory Type
GDDR5
Interface
PCI Express 3.0 x16
Form Factor
Half-length/Low-profile
Slot Space Required
Single Slot
Memory Bus Width
128-bit
Cooling Type
Fan Cooler
API Support
OpenCL 2.0, OpenGL 4.5, DirectX 12, Vulkan 1.0
Output Ports
4 x Mini DisplayPort
Supported Operating Systems
Linux, PC

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Pros & Cons

👍 Pros

  • Half-length, low-profile single-slot form factor enables installation in compact OEM workstations and small form factor chassis where no full-height professional GPU can physically fit.
  • Four simultaneous Mini DisplayPort outputs supporting 4K at 60Hz per display enables expansive multi-monitor professional desktop configurations from a single card.
  • No supplemental PCIe power connectors required — the card operates within the 75W PCIe slot budget, simplifying installation in systems without auxiliary GPU power routing.
  • 4GB GDDR5 on a 128-bit bus provides 96GB/s bandwidth, adequate for professional visualization and multi-display rendering within the constraints of the compact form factor.
  • OpenCL 2.0, OpenGL 4.5, DirectX 12, and Vulkan 1.0 support covers the full professional API surface for ISV-certified workstation application compatibility.

👎 Cons

  • 128-bit memory bus limits memory bandwidth to ~96GB/s — a constraint that surfaces in GPU-compute and complex 3D rendering tasks where wider-bus workstation cards deliver significantly higher throughput.
  • 1.13GHz base / 1.20GHz boost core clocks are modest for real-time viewport rendering in high-polygon CAD scenes where GPU core throughput becomes the limiting factor.
  • Mini DisplayPort outputs require adapters for HDMI or VGA displays — these are additional procurement items that add cost and potential compatibility friction in mixed-display environments.
  • Single-slot design limits thermal headroom: the card relies on a single fan cooler operating within constrained airflow, and sustained GPU-compute loads may cause the thermal solution to reach its limits faster than dual-slot alternatives.
  • CrossFire support, while listed, has no practical application in professional workstation use cases where ISV certifications cover single-GPU configurations only.

Frequently Asked Questions

The WX 4100 is a half-length, low-profile single-slot card. It will fit in both full-height ATX desktops (with the included low-profile bracket swap) and low-profile small form factor workstations designed for half-height cards. This dual-bracket compatibility is a significant deployment advantage for OEM compact workstation chassis where standard full-height cards physically cannot install.
The WX 4100 provides four Mini DisplayPort outputs and can drive four displays simultaneously. Maximum resolution per output over DisplayPort 1.4 is 4K (3840x2160) at 60Hz per display. Adapters are required for HDMI or VGA displays; Mini DP to DP, Mini DP to HDMI, and Mini DP to DVI adapters are widely available.
The WX 4100 supports OpenCL 2.0, OpenGL 4.5, DirectX 12, and Vulkan 1.0 — the full current professional API stack at its release. ISV certifications for professional applications (AutoCAD, Solidworks, Maya, etc.) are pursued through AMD's workstation driver program. Verify current certification status for your specific application version on AMD's ISV certification database, as certification approval timing varies by software release.
No — the WX 4100 operates entirely from PCIe slot power (75W maximum from the x16 slot), requiring no supplemental 6-pin or 8-pin PCIe power connectors. This simplifies installation in compact workstations and OEM systems that may not route auxiliary GPU power cables to the expansion area.
The 128-bit bus width paired with GDDR5 delivers approximately 96GB/s of memory bandwidth. For professional workstation workloads — CAD viewport rendering, 3D scene navigation, multi-display desktop management — this bandwidth level is appropriate for 4GB VRAM utilization at standard workstation resolutions. It becomes a constraint for GPU-accelerated compute workloads involving large datasets, where wider bus or HBM alternatives provide substantially higher throughput.